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Online GLP-1 programs, compared on what you really pay

Dozens of online programs prescribe semaglutide and tirzepatide, and the same medication can cost more than $100 a month more at one than at another. We compare each program on the prices it publishes, the medications it prescribes, the care you get and the terms behind the price.

By the RxLineup editorial team · 25 programs scored on 5 published criteria · Prices checked

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

The five highest-rated GLP-1 programs

Updated ·  · How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Our top pick for October 2026

01

Rated 9.1 out of 10, Excellent

Eden

Semaglutide $99/month, tirzepatide $129/month, at every dose. No membership fee.

From
$99/mo
Medications
Semaglutide, Tirzepatide Compounded, plus Wegovy, Ozempic, Zepbound, Mounjaro
Membership
None
  • Compounded semaglutide $99/month or tirzepatide $129/month at every dose
  • Price kept for as long as your account stays active
  • 24/7 provider support and messaging, with labwork when a provider orders it
Check eligibility with Eden (opens in a new tab)

on eden.health

Read the Eden review

Pricing details and fine print
Starting price
$99, compounded semaglutide, with provider care, 24/7 messaging and shipping included
Semaglutide / tirzepatide
$99/mo / $129/mo
Same price at every dose
Yes
Membership
No membership fee on the compounded GLP-1 plans: one monthly price covers the medication, provider care, 24/7 messaging and delivery. Brand-name GLP-1s need the Eden Membership ($39 for the first month, then $99 a month) on top of the medication.
Insurance
Eden and its providers don’t accept insurance. HSA and FSA cards accepted for most visits and prescriptions.
Guarantee
Weight Loss Warranty: follow your Eden plan for 6 months and, if you lose less than 15% of your body weight, you may qualify for your money back. Eligibility depends on plan adherence and required check-ins.
  1. 02
    Measured

    Low compounded prices, plus prior authorization help for brand-name GLP-1s

    Rated 9.0 out of 10, Excellent

  2. 03
    MEDGm

    Labs and video access included, with tablets and brand-name options

    Rated 9.0 out of 10, Excellent

  3. 04
    Gala GLP-1

    Coaching and app support at a low flat price

    Rated 8.8 out of 10, Excellent

  4. 05
    yourEra

    A low 12-month price that holds at every dose

    Rated 8.8 out of 10, Excellent

High-protein breakfast with yogurt, berries, eggs and toast

What it costs, provider by provider

The same treatment can cost very different amounts from one provider to the next. Each figure here takes one price per provider, the lowest it publishes with medication included, read from its own site on Nov 3, 2026.

See every provider’s price

Prices across the programs we compare, checked Nov 3, 2026
Treatment Per month
Compounded semaglutide Lowest to highest at the 20 programs that publish one; median $173.50 $65–$299/mo
Compounded tirzepatide Lowest to highest at the 20 programs that publish one; median $244.50 $85.58–$378.08/mo

Prices as advertised on each provider’s site, medication included; a sale counts at its regular price. Confirm the price with the provider before you pay.

Ranked for every need

A provider keeps the same published score on every list. Each list is filtered and ordered for one need.

Treatments, explained

What each one is, whether it is FDA-approved, how you take it and the lowest price we found.

  • Wegovy®

    FDA-approved

    Weekly injection

    From $448/mo at the providers we track

  • Wegovy® pill

    FDA-approved

    Daily pill

    From $198/mo at the providers we track

  • Zepbound®

    FDA-approved

    Weekly injection (vial or KwikPen)

    From $398/mo at the providers we track

  • Foundayo™

    FDA-approved

    Daily pill

    From $248/mo at the providers we track

  • Ozempic®

    FDA-approved; prescribed off-label here

    Weekly injection

    From $448/mo at the providers we track

  • Mounjaro®

    FDA-approved; prescribed off-label here

    Weekly injection

    From $1,261.42/mo at the providers we track

  • Daily injection

  • Semaglutide

    Sold as Wegovy (weight loss), Ozempic and Rybelsus (type 2 diabetes)

    Weekly injection or daily pill

    Compounded semaglutide from $65/mo at the providers we track

  • Tirzepatide

    Sold as Zepbound (weight loss, sleep apnea) and Mounjaro (type 2 diabetes)

    Weekly injection

    Compounded tirzepatide from $85.58/mo at the providers we track

  • Compounded GLP-1s

    Compounded; not FDA-approved

    Injection (vial) or tablet

    Compounded semaglutide from $65/mo at the providers we track

Weight loss guides, with sources

All guides

Insurance

Does insurance cover Ozempic?

Plans look at your diagnosis first. How commercial plans, Medicare Part D, Medicaid and TRICARE handle Ozempic, and what it costs with and without coverage.

6 min read

Safety

One of these treatments carries an FDA boxed warning, the strongest warning on a label: GLP-1 medications.

SemaglutideNot FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2. FDA label
TirzepatideNot FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2. FDA label
WegovyFDA-approved for long-term weight reduction (adults, and children 12 and older)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
OzempicFDA-approved drug; used off-label here
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
ZepboundFDA-approved for long-term weight reduction (adults)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
MounjaroFDA-approved drug; used off-label here
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
Wegovy pillFDA-approved for long-term weight reduction (adults)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
Compounded GLP-1sCompounded; not FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality.

Questions, answered

How much does a GLP-1 weight loss program cost?

At the programs we compare that publish a price, compounded semaglutide costs $65 to $299 a month and compounded tirzepatide $85.58 to $378.08 a month, with medication included, as of November 3, 2026. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. The weight loss price index lists every provider’s price.

How much does compounded semaglutide cost online?

At the 20 programs we compare that publish a price, compounded semaglutide costs $65 to $299 a month with medication included, and the median is $173.50, as of November 3, 2026. The weight loss price index lists every provider’s price.

Which online GLP-1 program is best?

Our top pick for October 2026 is Eden, with a score of 9.1 out of 10. Choose Eden for a low flat price that holds as your dose rises: $99 a month for semaglutide or $129 for tirzepatide, with no membership and no contract. Its warranty refunds you if you follow the plan and lose less than 15% in 6 months, subject to its terms. Scores and the order of each list come from our published rating method.

How do online GLP-1 programs work?

You answer an online health questionnaire, a licensed clinician reviews it (sometimes over a video or phone visit), and if a treatment suits you, a licensed pharmacy ships it to your door. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality.

How does RxLineup make money?

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. Scores and the order of each list come from our published rating method.

Not sure which program fits?

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