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The best NAD+ nasal spray providers online in 2026

NAD+ nasal spray is a needle-free alternative to injections.NAD+ nasal spray is a needle-free alternative to injections. Like the injection, it is compounded by a licensed pharmacy and isn’t FDA-approved, and no trial has compared the two routes.

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

At a glance

Program Score
Top pick Eden NAD+ nasal spray from $226/mo, 3-month plan 8.1
Best value RxSpan MD NAD+ nasal spray from $150/mo, 12 mo prepaid 8.0

By the RxLineup editorial team · 2 providers scored on 5 published criteria · Prices checked

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure

Our top pick for October 2026

01

Rated 8.1 out of 10, Good

Eden

NAD+ nasal spray from $226/mo, on a 3-month plan ($127 + $99/mo membership).

NAD+ nasal spray from
$226/mo $127 + $99/mo membershipon a 3-month plan
Treatments
NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione Compounded All 6 treatments
Membership
$99/mo
  • NAD+ as an injection or nasal spray; sermorelin as an injection or under-the-tongue tablet
  • NAD+ prices published by vial size and plan length, including the price after the first month
  • Free expedited 2-day shipping from the pharmacy
Check eligibility with Eden (opens in a new tab)

on eden.health

Read the Eden review

Pricing details and fine print
Starting price
$186, NAD+ injections (500 mg vial) a month on the 3-month plan after a $119 first month, medication only; the required membership is $39 for the first month, then $99 a month; $285/mo all-in
Terms
3-month plan
NAD+ injections
$285/mo, on a 3-month plan
Sermorelin
$126 for the first month + $99/mo membership
Rapamycin
Not offered
Membership
Required: $39 for the first month, then $99 a month. Medication is billed separately and isn’t available without a membership. The $39 first fee is refunded if no prescription is issued.
Insurance
Doesn’t take insurance; HSA and FSA cards accepted for most visits and prescriptions.
Guarantee
If a provider decides treatment isn’t right for you and no prescription is issued, Eden refunds the $39 first membership fee.
02

Best value

Rated 8.0 out of 10, Good

RxSpan MD

NAD+ nasal spray from $150/mo, billed $1,800 for 12 months.

NAD+ nasal spray from
$150/mo billed $1,800 for 12 months
Treatments
NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione Compounded All 6 treatments
Membership
None
  • Consult, medication, supplies, shipping and support in each plan price
  • Unlimited appointments and messaging with the care team
  • Monthly, 3-month, 6-month and 12-month prepaid plans, lower per month on longer plans
Check eligibility with RxSpan MD (opens in a new tab)

on rxspanmd.com

Read the RxSpan MD review

Pricing details and fine print
Starting price
$142, sermorelin under-the-tongue tablets a month on a prepaid 12-month plan ($179 month to month), with the consult, medication, supplies and shipping included
Terms
12-month plan, prepaid (billed $1,800 for 12 months)
NAD+ injections
$150/mo, billed $1,800 for 12 months
Sermorelin
$142/mo, billed $1,704 for 12 months
Rapamycin
Not offered
Membership
No membership fee shown; each plan price includes the consult, medication, supplies, shipping and support.
Insurance
No insurance billing listed; financing plans available.

Prices are as each provider advertised them when we checked and can change at any time. NAD+ injections and sermorelin are compounded and are not FDA-approved for anti-aging. Evidence for anti-aging benefits is limited. A prescription is required and is at the clinician’s discretion.

Compare every provider

All 2 providers on price, treatments and terms. Select a name for the full review.

All 2 providers in this ranking compared
Provider Eden review RxSpan MD review
Our score 8.1/10 Highest 8.0/10
NAD+ nasal spray $226/mo $127 + $99/mo membership; on a 3-month plan $150/mo billed $1,800 for 12 months Lowest
NAD+ injections $285/mo $186 + $99/mo membership; on a 3-month plan $150/mo billed $1,800 for 12 months Lowest
Sermorelin $126 for the first month + $99/mo membership $142/mo billed $1,704 for 12 months
Rapamycin Not offered Not offered
Treatments NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione, Methylene blue, Vitamin B12 and lipotropic injections NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione, Methylene blue, Vitamin B12 and lipotropic injections
Membership $99/mo None Lowest
Insurance Self-pay –
Next step Visit site for Eden (opens in a new tab) Visit site for RxSpan MD (opens in a new tab)

– Not published by the provider.

What it costs

  • 2 of the 2 providers here publish an all-in monthly price for nad+ nasal spray: $150 to $226 a month, with a median of $188. That includes the medication and any membership the provider requires.
  • 2 of these prices need a prepaid or fixed plan of 3 months or more; each says so beside the price.
  • A sale counts at its regular price, with the sale price shown beside it.

Every provider’s price, side by side: the longevity price index.

Safety

NAD+Compounded; not FDA-approved
There is no FDA label, and compounded NAD+ isn’t FDA-reviewed for safety, effectiveness or quality.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

How we rated these providers

Every provider gets the same five weighted scores, and this list runs from the highest score down.

  1. Price & value 30%
  2. Clinical care 25%
  3. Medication options 20%
  4. Transparency 15%
  5. Experience 10%

The providers on this page pay us when you sign up through our links. How we rate

Plain shipping box on a sunny front step

The bottom line

Our top pick is Eden

Eden has the highest overall score on this list, 8.1 out of 10. NAD+ nasal spray there costs $226/mo, on a 3-month plan ($127 + $99/mo membership).

Check eligibility with Eden (opens in a new tab) Read the review of Eden

Rated 8.1 out of 10, Good

From $226/mo NAD+ nasal spray: $127 + $99/mo membership on a 3-month plan

How online longevity treatment works

Online longevity clinics sell treatments such as NAD+ injections and sermorelin, usually compounded and often with lab panels. The evidence behind many of them is limited, so we compare prices and clinical oversight and say plainly what each treatment is and isn’t approved for.

You fill in a health questionnaire on the provider’s own site. A licensed clinician reviews it, often with lab results, and decides whether a treatment is right for you. If you are prescribed, a licensed pharmacy ships it, and most providers renew the prescription on a subscription.

Which treatment is which

Scroll sideways to see the full table

Treatment Active ingredient Form Status
NAD+ Nicotinamide adenine dinucleotide (NAD+) Subcutaneous injection or nasal spray Compounded; not FDA-approved
Sermorelin Sermorelin acetate (growth hormone-releasing hormone 1-29) Subcutaneous injection; also nasal spray, troche, lozenge or under-the-tongue tablet Compounded; not FDA-approved
Glutathione Glutathione (reduced, GSH) Injection; also nasal spray and rapid-dissolve tablet Compounded; not FDA-approved
Metformin for longevity Metformin hydrochloride Tablet (immediate or extended release) FDA-approved; off-label here
Rapamycin (sirolimus) Sirolimus Tablet (generic) or compounded capsule FDA-approved; off-label here
Low-dose naltrexone (LDN) Naltrexone hydrochloride Capsule, tablet or troche Compounded; not FDA-approved
Methylene blue Methylthioninium chloride Oral capsule (compounded) Compounded; not FDA-approved
Vitamin B12 and lipotropic (MIC) injections Cyanocobalamin or methylcobalamin, often with methionine, inositol and choline Injection Compounded; not FDA-approved

FDA-approved or compounded?

FDA-approved products, including generics, are made by their manufacturers to an approved standard. Compounded products are prepared by state-licensed pharmacies for an individual prescription, often to combine ingredients or change the form. They are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality.

NAD+ injections and sermorelin are compounded and are not FDA-approved for anti-aging. Evidence for anti-aging benefits is limited.

What to look for in a provider

  • The monthly price for the treatment you want, and what it covers: the consult, refills and shipping.
  • A real clinical review. A licensed clinician should review your history before prescribing and order lab tests where the treatment calls for them.
  • A licensed US pharmacy, and a clear statement of which products are FDA-approved and which are compounded.
  • Terms you can live with. Check the subscription length, how to cancel and what happens if you are not prescribed.

Compare every longevity clinic side by side

See every longevity clinic’s score, monthly price and fine print on one page, ordered by our published rating method.

See all rankings

Questions, answered

How much does NAD+ nasal spray cost?
NAD+ nasal spray costs $150 to $226 a month with medication and any required membership included, at the 2 clinics on this page that publish an ongoing monthly price (as of October 2026).

Is NAD+ nasal spray as good as injections?
Nobody knows. No published trial has compared NAD+ nasal spray with injections, or tested either one for aging. Clinics offer the spray mainly for people who would rather avoid needles.

How do you use NAD+ nasal spray?
As your prescription directs, usually one or more sprays in each nostril once or twice a day. Prime the pump first and keep the bottle as the pharmacy label says.

What are the side effects of NAD+ nasal spray?
Little has been published. Ask your prescriber what to watch for, and stop and get advice if you have nosebleeds, lasting irritation or headaches.

Does NAD+ nasal spray need a prescription?
From these clinics, yes. It is a compounded drug prepared by a pharmacy for your prescription, and it isn’t FDA-approved for any use.

How long does a bottle of NAD+ nasal spray last?
It depends on the strength and your dose, and clinics don’t all publish it. Ask how many weeks a bottle covers so you can compare the monthly cost.

Guides

Sources (prices checked Oct 31, 2026)

  1. Eden: homepage (read Oct 26, 2026)
  2. RxSpan MD: Longevity page (read Oct 26, 2026)

Top pick · Eden

8.1/10 ·  From $226/mo, 3-month plan

Check eligibility with Eden (opens in a new tab)