Medical disclaimer
Last updated
Information on RxLineup is for general information and comparison only. It is not medical advice, diagnosis or treatment, and it is not a substitute for advice from a qualified healthcare professional who knows your history.
Prescription treatments
The treatments we compare, for weight loss, erectile dysfunction, hair loss, low testosterone, menopause, skin care, longevity and peptides, are prescription products. Whether one is appropriate for you is a decision for a licensed clinician after reviewing your health history, and a provider may decline to prescribe. Never start, stop or change a medication based on something you read here.
Boxed warnings and side effects
Some of these medications carry an FDA boxed warning, the strongest warning on a label: GLP-1 medications for thyroid C-cell tumors, estrogen for endometrial cancer and other risks, testosterone gels for secondary exposure of children, and others. Where a page ranks or sells a treatment with a boxed warning, it says so and links to the treatment’s safety information. Our summaries don’t list every risk; read the full prescribing information and ask your clinician.
Controlled substances
Testosterone is a Schedule III controlled substance. Prescribing it online without an in-person exam relies on a temporary DEA and HHS telemedicine rule that runs through December 31, 2026, and it requires a live video visit with the prescriber and blood tests before you start. A phone call alone doesn’t meet that rule. The rule can change, and so can what online providers are allowed to prescribe.
Off-label use
Some treatments we describe are prescribed off-label, for a use the FDA hasn’t approved them for: for example Ozempic and Mounjaro for weight loss, low-dose oral minoxidil for hair loss, testosterone for women, rapamycin and metformin for longevity, and sertraline or paroxetine for premature ejaculation. Off-label prescribing is legal and common, but the evidence for the off-label use is usually more limited than for the approved one, and we say when a use is off-label.
Hormone therapy
Menopause hormone therapy and testosterone therapy have benefits and risks that depend on your age, health history and the product. Estrogen taken without a progestogen by a woman with a uterus raises the risk of endometrial cancer. Decisions about hormone therapy, and how long to take it, belong with a clinician who knows your history.
Compounded medications and peptides
Compounded drugs are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before they are marketed. Compounded semaglutide and tirzepatide are not Wegovy, Ozempic, Zepbound or Mounjaro, and not generics of them; a compounding pharmacy prepares them for a prescription. Many peptides sold online have no FDA approval for any use, and the FDA has restricted which ones pharmacies may compound. We don’t list research chemicals, or peptides that pharmacies may not lawfully compound.
Results
Weight loss and other results on this site are averages from clinical trials of FDA-approved medications, as reported on their labels or in the published trials. Individual results vary, and results from compounded medications, or from off-label uses, have not been established in those trials.
Emergencies
If you think you may have a medical emergency, call 911 or your local emergency number right away.