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Longevity clinics online, compared with the evidence

Online longevity clinics sell treatments such as NAD+ injections and sermorelin, usually compounded and often with lab panels. The evidence behind many of them is limited, so we compare prices and clinical oversight and say plainly what each treatment is and isn’t approved for.

By the RxLineup editorial team · 6 clinics scored on 5 published criteria · Prices checked

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

Safety: boxed warnings apply to rapamycin (sirolimus) and methylene blue. Read before you start

The five highest-rated longevity clinics

Updated ·  · How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure

Our top pick for October 2026

01

Rated 8.6 out of 10, Very good

Strut Health

Oral sermorelin $99 a month for 30 lozenges; injectable sermorelin $119 a month.

From
$99/mo
Treatments
Sermorelin, NAD+ injections Compounded
Membership
None
  • Physicians by secure chat, phone or video
  • Message a physician any time; follow-ups are free
  • Free, discreet shipping, typically within 2 business days
Check eligibility with Strut Health (opens in a new tab)

on struthealth.com

Read the Strut Health review

Pricing details and fine print
Starting price
$99, oral sermorelin, 30 lozenges a month on auto-refill; injectable sermorelin $119 a month
NAD+ injections
$149/mo
Sermorelin
$99/mo
Rapamycin
Not offered
Membership
No membership; prices include physician consultations and free shipping.
Insurance
Cash pay; Strut doesn’t bill insurance.
Availability
All states except Arkansas; some medications vary by state
  1. 02
    yourEra

    Regular check-ins and a live visit whenever you want one

    Rated 8.5 out of 10, Very good

    From $170/mo

    Visit site for yourEra (opens in a new tab)
  2. 03
    EverPrime

    Sermorelin with IGF-1 labs every 6 months

    Rated 8.4 out of 10, Very good

    From $169/mo

    Visit site for EverPrime (opens in a new tab)
  3. 04
    Embody

    Sermorelin at one flat all-in monthly price, with the pharmacies named

    Rated 8.3 out of 10, Very good

    From $149/mo On sale now: $99/mo† † Sale price; regularly $149

    Visit site for Embody (opens in a new tab)
  4. 05
    Eden

    Needle-free NAD+ and sermorelin, with follow-up visits in the membership

    Rated 8.1 out of 10, Good

    From $285/mo $186 + $99/mo membership on a 3-month plan

    Visit site for Eden (opens in a new tab)
All 6 clinics, ranked Longevity price index

Popular reviews

Across every category: Strut Health, yourEra, EverPrime, Embody, Eden, RxSpan MD

Small glass vial beside a glass of water

What it costs, provider by provider

The same treatment can cost very different amounts from one provider to the next. Each figure here takes one price per provider, the lowest it publishes with medication included, read from its own site on Oct 31, 2026.

See every provider’s price

Prices across the clinics we compare, checked Oct 31, 2026
Treatment Per month
NAD+ injections Lowest to highest at the 5 clinics that publish one; median $153 $149–$285/mo
Sermorelin Lowest to highest at the 4 clinics that publish one; median $145.50 $99–$149/mo

Prices as advertised on each provider’s site, medication included; a sale counts at its regular price. Confirm the price with the provider before you pay.

Ranked for every need

A provider keeps the same published score on every list. Each list is filtered and ordered for one need. Strut Health tops 2 of these 3 lists.

Treatments, explained

What each one is, whether it is FDA-approved, how you take it and the lowest price we found.

  • NAD+

    Compounded; not FDA-approved

    Subcutaneous injection or nasal spray

    NAD+ injections from $149/mo at the providers we track

  • Sermorelin

    Compounded; not FDA-approved

    Subcutaneous injection; also nasal spray, troche, lozenge or under-the-tongue tablet

    From $99/mo at the providers we track

  • Glutathione

    Compounded; not FDA-approved

    Injection; also nasal spray and rapid-dissolve tablet

    From $149/mo at the providers we track

  • Metformin for longevity

    FDA-approved; prescribed off-label here

    Tablet (immediate or extended release)

  • Rapamycin (sirolimus)

    FDA-approved; prescribed off-label here

    Tablet (generic) or compounded capsule

  • Low-dose naltrexone (LDN)

    Compounded; not FDA-approved

    Capsule, tablet or troche

  • Methylene blue

    Compounded; not FDA-approved

    Oral capsule (compounded)

    From $99/mo at the providers we track

  • Vitamin B12 and lipotropic (MIC) injections

    Compounded; not FDA-approved

    Injection

    From $100/mo at the providers we track

Longevity guides, with sources

All guides

Safety

2 of these treatments carry an FDA boxed warning, the strongest warning on a label: rapamycin (sirolimus) and methylene blue.

Rapamycin (sirolimus)FDA-approved drug; used off-label here
Boxed warning: immunosuppression. Increased susceptibility to infection and the possible development of lymphoma may result from immunosuppression (the label also warns against use in liver or lung transplant patients). FDA label
Methylene blueCompounded; not FDA-approved
Boxed warning: serotonin syndrome with serotonergic drugs and opioids.
NAD+Compounded; not FDA-approved
There is no FDA label, and compounded NAD+ isn’t FDA-reviewed for safety, effectiveness or quality.
SermorelinCompounded; not FDA-approved
Compounded sermorelin isn’t FDA-reviewed for safety, effectiveness or quality, and its old Geref labeling covered children, not adults using it for aging.
GlutathioneCompounded; not FDA-approved
There is no FDA label for injectable glutathione, and compounded glutathione isn’t FDA-reviewed for safety, effectiveness or quality.
Vitamin B12 and lipotropic (MIC) injectionsCompounded; not FDA-approved
The cyanocobalamin label warns of anaphylaxis, which has been fatal, after injected B12; of low potassium when severe anemia is treated intensely; and of rapid optic nerve damage in people with early Leber’s disease.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

NAD+ injections and sermorelin are compounded and are not FDA-approved for anti-aging. Evidence for anti-aging benefits is limited.

Questions, answered

How much do NAD+ injections cost online?
At the 5 clinics we compare that publish a price, NAD+ injections cost $149 to $285 a month with medication included, and the median is $153, as of October 31, 2026. The longevity price index lists every provider’s price.

Which online longevity clinic is best?
Our top pick for October 2026 is Strut Health, with a score of 8.6 out of 10. Good value for sermorelin, with a $99 lozenge option and physicians you can reach by chat, phone or video. Each price is monthly on auto-refill, with the physician and shipping included. Scores and the order of each list come from our published rating method.

How do online longevity clinics work?
You answer an online health questionnaire, a licensed clinician reviews it (sometimes over a video or phone visit), and if a treatment suits you, a licensed pharmacy ships it to your door. NAD+ injections and sermorelin are compounded and are not FDA-approved for anti-aging. Evidence for anti-aging benefits is limited.

How does RxLineup make money?
Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. Scores and the order of each list come from our published rating method.