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The best online longevity clinics in 2026

Online longevity clinics prescribe treatments such as NAD+ injections, sermorelin and rapamycin, and the same treatment can cost twice as much at one clinic as at another once memberships are added.

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

  • Safety: Methylene blue carries a boxed warning for serotonin syndrome when taken with serotonergic drugs. Read before you start

At a glance

Program Score
Top pick Strut Health From $99/mo 8.6
Best clinical care yourEra From $170/mo 8.5
Most options EverPrime From $169/mo 8.4

By the RxLineup editorial team · 6 providers scored on 5 published criteria · Prices checked

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure

Our top pick for October 2026

01

Rated 8.6 out of 10, Very good

Strut Health

Oral sermorelin $99 a month for 30 lozenges; injectable sermorelin $119 a month.

From
$99/mo
Treatments
Sermorelin, NAD+ injections Compounded
Membership
None
  • Physicians by secure chat, phone or video
  • Message a physician any time; follow-ups are free
  • Free, discreet shipping, typically within 2 business days
Check eligibility with Strut Health (opens in a new tab)

on struthealth.com

Read the Strut Health review

Pricing details and fine print
Starting price
$99, oral sermorelin, 30 lozenges a month on auto-refill; injectable sermorelin $119 a month
NAD+ injections
$149/mo
Sermorelin
$99/mo
Rapamycin
Not offered
Membership
No membership; prices include physician consultations and free shipping.
Insurance
Cash pay; Strut doesn’t bill insurance.
Availability
All states except Arkansas; some medications vary by state
02

Best clinical care

Rated 8.5 out of 10, Very good

yourEra

NAD+ therapy from $170/month, with the visit, medication and shipping included.

From
$170/mo
Treatments
NAD+ injections, Sermorelin Compounded
Membership
None
  • Provider evaluation, personalized protocol, medication, supplies and check-ins in one price
  • A live video or phone visit on request, at no extra charge
  • Message your care team anytime from the patient portal
Check eligibility with yourEra (opens in a new tab)

on yourera.com

Read the yourEra review

Pricing details and fine print
Starting price
$170, NAD+ therapy a month, with the provider evaluation, medication, supplies, check-ins and shipping included
NAD+ injections
$170/mo
Sermorelin
Price not published
Rapamycin
Not offered
Membership
No membership needed. An optional Optimum membership with coaching and at-home labs is listed as coming soon.
Insurance
Doesn’t bill insurance; it says many members use HSA or FSA funds.
Guarantee
You aren’t charged unless a clinician issues a prescription, and you get a full refund if you cancel before your order ships.
Availability
All 50 states (availability of specific treatments varies by state)
03

Most options

Rated 8.4 out of 10, Very good

EverPrime

Sermorelin $169 a month, or $149 a month on a 6-month plan; NAD+ injections from $153 a month on 12 months.

From
$169/mo
Treatments
Sermorelin, NAD+ injections Compounded
Membership
None
  • Licensed provider evaluation and ongoing treatment reviews
  • IGF-1 lab testing every 6 months on sermorelin (in New York, New Jersey and Rhode Island, a $50 lab discount instead)
  • Syringes, needles and alcohol swabs
Check eligibility with EverPrime (opens in a new tab)

on joineverprime.com

Read the EverPrime review

Pricing details and fine print
Starting price
$169, sermorelin injections on a 1-month plan without a membership ($149 a month on a 6-month plan paid up front)
NAD+ injections
$153/mo, billed $1,836 for 12 months
Sermorelin
$149/mo, billed $894 for 6 months
Rapamycin
Not offered
Membership
No membership required. An optional $99 a month membership lowers sermorelin to $139 to $129 a month and NAD+ to $115 to $99, which with the fee costs more than the standard price, and adds provider and nutrition visits and partner discounts.
Insurance
Cash pay; its terms say its services can’t be billed to Medicare, Medicaid or other government programs. HSA and FSA accepted for eligible expenses.
Guarantee
Full refund if your provider decides treatment isn’t right for you.
Availability
Not available in every state
04

Rated 8.3 out of 10, Very good

Embody

Pre-Black Friday sale: sermorelin $49 for the first month, then $99 a month (regular price $149 a month).

From
$149/mo On sale now: $99/mo†† Sale price; regularly $149
Treatments
Sermorelin Compounded
Membership
None
  • Free online medical evaluation, and a refund if you aren’t eligible
  • Medication, supplies, the doctor review and shipping in one monthly price
Check eligibility with Embody (opens in a new tab)

on joinem.co

Read the Embody review

Pricing details and fine print
Starting price
$99, sermorelin injections, Pre-Black Friday sale price after a $49 first month (regularly $149), with medication, the doctor review and shipping included
NAD+ injections
Not offered
Sermorelin
$99/mo†. † Sale price; regularly $149
Rapamycin
Not offered
Membership
No membership fees; the monthly price covers medication, supplies, the doctor review and shipping.
Insurance
No insurance needed; its pages don’t say it bills insurance.
Guarantee
Refund if a provider decides you aren’t eligible, less the value of any services already given. Other payments are final.
Availability
All US states except Louisiana (Nebraska: 19 and older)
05

Rated 8.1 out of 10, Good

Eden

NAD+ injections from $285/mo, on a 3-month plan ($186 + $99/mo membership).

From
$285/mo $186 + $99/mo membershipon a 3-month plan
Treatments
NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione Compounded All 6 treatments
Membership
$99/mo
  • NAD+ as an injection or nasal spray; sermorelin as an injection or under-the-tongue tablet
  • NAD+ prices published by vial size and plan length, including the price after the first month
Check eligibility with Eden (opens in a new tab)

on eden.health

Read the Eden review

Pricing details and fine print
Starting price
$186, NAD+ injections (500 mg vial) a month on the 3-month plan after a $119 first month, medication only; the required membership is $39 for the first month, then $99 a month; $285/mo all-in
Terms
3-month plan
NAD+ injections
$285/mo, on a 3-month plan
Sermorelin
$126 for the first month + $99/mo membership
Rapamycin
Not offered
Membership
Required: $39 for the first month, then $99 a month. Medication is billed separately and isn’t available without a membership. The $39 first fee is refunded if no prescription is issued.
Insurance
Doesn’t take insurance; HSA and FSA cards accepted for most visits and prescriptions.
Guarantee
If a provider decides treatment isn’t right for you and no prescription is issued, Eden refunds the $39 first membership fee.
06

Rated 8.0 out of 10, Good

RxSpan MD

Sermorelin tablets from $142/month and NAD+ injections from $150/month on a 12-month plan.

From
$142/mo billed $1,704 for 12 months
Treatments
NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione Compounded All 6 treatments
Membership
None
  • Consult, medication, supplies, shipping and support in each plan price
  • Unlimited appointments and messaging with the care team
Check eligibility with RxSpan MD (opens in a new tab)

on rxspanmd.com

Read the RxSpan MD review

Pricing details and fine print
Starting price
$142, sermorelin under-the-tongue tablets a month on a prepaid 12-month plan ($179 month to month), with the consult, medication, supplies and shipping included
Terms
12-month plan, prepaid (billed $1,704 for 12 months)
NAD+ injections
$150/mo, billed $1,800 for 12 months
Sermorelin
$142/mo, billed $1,704 for 12 months
Rapamycin
Not offered
Membership
No membership fee shown; each plan price includes the consult, medication, supplies, shipping and support.
Insurance
No insurance billing listed; financing plans available.

Prices are as each provider advertised them when we checked and can change at any time. NAD+ injections and sermorelin are compounded and are not FDA-approved for anti-aging. Evidence for anti-aging benefits is limited. A prescription is required and is at the clinician’s discretion.

Compare every provider

All 6 providers on price, treatments and terms. Select a name for the full review.

Scroll sideways to see all 6 providers

All 6 providers in this ranking compared
Provider Strut Health review yourEra review EverPrime review Embody review Eden review RxSpan MD review
Our score 8.6/10 Highest 8.5/10 8.4/10 8.3/10 8.1/10 8.0/10
Starting price $99/mo Lowest $170/mo $169/mo $149/mo on sale now: $99/mo† $285/mo $186 + $99/mo membership; on a 3-month plan $142/mo billed $1,704 for 12 months
NAD+ injections $149/mo Lowest $170/mo $153/mo billed $1,836 for 12 months Not offered $285/mo $186 + $99/mo membership; on a 3-month plan $150/mo billed $1,800 for 12 months
Sermorelin $99/mo Lowest – $149/mo billed $894 for 6 months $149/mo on sale now: $99/mo† $126 for the first month + $99/mo membership $142/mo billed $1,704 for 12 months
Rapamycin Not offered Not offered Not offered Not offered Not offered Not offered
Treatments Sermorelin, NAD+ injections NAD+ injections, Sermorelin Sermorelin, NAD+ injections Sermorelin NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione, Methylene blue, Vitamin B12 and lipotropic injections NAD+ injections, NAD+ nasal spray, Sermorelin, Glutathione, Methylene blue, Vitamin B12 and lipotropic injections
Membership None None None None $99/mo None
Insurance Self-pay Self-pay Self-pay – Self-pay –
Next step Visit site for Strut Health (opens in a new tab) Visit site for yourEra (opens in a new tab) Visit site for EverPrime (opens in a new tab) Visit site for Embody (opens in a new tab) Visit site for Eden (opens in a new tab) Visit site for RxSpan MD (opens in a new tab)

† Embody: Sale price; regularly $149.

– Not published by the provider.

What it costs

  • 6 of the 6 providers here publish an all-in monthly starting price: $99 to $285 a month, with a median of $159. That includes the medication and any membership the provider requires.
  • 2 of these prices need a prepaid or fixed plan of 3 months or more; each says so beside the price.
  • A sale counts at its regular price, with the sale price shown beside it.

Every provider’s price, side by side: the longevity price index.

Safety

One of these treatments carries an FDA boxed warning, the strongest warning on a label: methylene blue.

Methylene blueCompounded; not FDA-approved
Boxed warning: serotonin syndrome with serotonergic drugs and opioids.
SermorelinCompounded; not FDA-approved
Compounded sermorelin isn’t FDA-reviewed for safety, effectiveness or quality, and its old Geref labeling covered children, not adults using it for aging.
NAD+Compounded; not FDA-approved
There is no FDA label, and compounded NAD+ isn’t FDA-reviewed for safety, effectiveness or quality.
GlutathioneCompounded; not FDA-approved
There is no FDA label for injectable glutathione, and compounded glutathione isn’t FDA-reviewed for safety, effectiveness or quality.
Vitamin B12 and lipotropic (MIC) injectionsCompounded; not FDA-approved
The cyanocobalamin label warns of anaphylaxis, which has been fatal, after injected B12; of low potassium when severe anemia is treated intensely; and of rapid optic nerve damage in people with early Leber’s disease.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

How we rated these providers

Every provider gets the same five weighted scores, and this list runs from the highest score down.

  1. Price & value 30%
  2. Clinical care 25%
  3. Medication options 20%
  4. Transparency 15%
  5. Experience 10%

The providers on this page pay us when you sign up through our links. How we rate

Plain shipping box on a sunny front step

The bottom line

Our top pick is Strut Health

Good value for sermorelin, with a $99 lozenge option and physicians you can reach by chat, phone or video. Each price is monthly on auto-refill, with the physician and shipping included.

Check eligibility with Strut Health (opens in a new tab) Read the review of Strut Health

Rated 8.6 out of 10, Very good

From $99/mo Oral sermorelin, 30 lozenges a month on auto-refill; injectable sermorelin $119 a month

How online longevity treatment works

Online longevity clinics sell treatments such as NAD+ injections and sermorelin, usually compounded and often with lab panels. The evidence behind many of them is limited, so we compare prices and clinical oversight and say plainly what each treatment is and isn’t approved for.

You fill in a health questionnaire on the provider’s own site. A licensed clinician reviews it, often with lab results, and decides whether a treatment is right for you. If you are prescribed, a licensed pharmacy ships it, and most providers renew the prescription on a subscription.

Which treatment is which

Scroll sideways to see the full table

Treatment Active ingredient Form Status
NAD+ Nicotinamide adenine dinucleotide (NAD+) Subcutaneous injection or nasal spray Compounded; not FDA-approved
Sermorelin Sermorelin acetate (growth hormone-releasing hormone 1-29) Subcutaneous injection; also nasal spray, troche, lozenge or under-the-tongue tablet Compounded; not FDA-approved
Glutathione Glutathione (reduced, GSH) Injection; also nasal spray and rapid-dissolve tablet Compounded; not FDA-approved
Metformin for longevity Metformin hydrochloride Tablet (immediate or extended release) FDA-approved; off-label here
Rapamycin (sirolimus) Sirolimus Tablet (generic) or compounded capsule FDA-approved; off-label here
Low-dose naltrexone (LDN) Naltrexone hydrochloride Capsule, tablet or troche Compounded; not FDA-approved
Methylene blue Methylthioninium chloride Oral capsule (compounded) Compounded; not FDA-approved
Vitamin B12 and lipotropic (MIC) injections Cyanocobalamin or methylcobalamin, often with methionine, inositol and choline Injection Compounded; not FDA-approved

FDA-approved or compounded?

FDA-approved products, including generics, are made by their manufacturers to an approved standard. Compounded products are prepared by state-licensed pharmacies for an individual prescription, often to combine ingredients or change the form. They are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality.

NAD+ injections and sermorelin are compounded and are not FDA-approved for anti-aging. Evidence for anti-aging benefits is limited.

What to look for in a provider

  • The monthly price for the treatment you want, and what it covers: the consult, refills and shipping.
  • A real clinical review. A licensed clinician should review your history before prescribing and order lab tests where the treatment calls for them.
  • A licensed US pharmacy, and a clear statement of which products are FDA-approved and which are compounded.
  • Terms you can live with. Check the subscription length, how to cancel and what happens if you are not prescribed.

Questions, answered

What is the best online longevity clinic?
It depends on the treatment you want. Our ranked list scores each clinic on all-in price, clinical care, treatment options, transparency and experience. Clinics that include medication, care and shipping in one monthly price score higher on value than those that add a membership on top, and clinics that include lab work score higher on care for treatments such as rapamycin.

Do longevity treatments actually work?
No treatment sold by these clinics has been shown to extend lifespan or slow aging in people. Rapamycin extends lifespan in mice, and a 48-week human trial found low weekly doses relatively safe but did not change its main outcome. NAD+ injections and sermorelin have only small, short human studies. Read is longevity medicine legit? for what is and isn’t proven.

How much do online longevity clinics cost?
The lowest ongoing price for NAD+ injections is Strut Health’s, at $149 a month. The lowest ongoing price for sermorelin is Strut Health’s, at $99 a month. Memberships at the clinics that require one run $99 a month, and every figure here already includes it. Each treatment page on this site lists the full range.

Are NAD+ and sermorelin FDA-approved?
No. Compounded NAD+ and sermorelin are not FDA-approved. A licensed pharmacy prepares them for your prescription. NAD+ is compounded under an interim FDA policy (Category 1 of its 503A list), and sermorelin was once sold as the approved drug Geref, which was discontinued in 2008. Rapamycin and metformin are FDA-approved drugs, but using them for aging is off-label.

Do online longevity clinics require lab work?
Some do. Rapamycin is usually prescribed after baseline labs, and a few clinics start every member with a blood panel; others prescribe NAD+ or sermorelin after a questionnaire alone. Each listing’s review says what it requires.

Is rapamycin safe to take for longevity?
Rapamycin (sirolimus) is an immunosuppressant, and its transplant label carries a boxed warning for serious infections and cancer at transplant doses. Clinics prescribe much lower, often weekly, doses off-label; small trials such as PEARL found no serious safety signal over about a year, but no proven benefit for aging.

Guides

Sources (prices checked Oct 31, 2026)

  1. Strut Health: Oral page (read Oct 18, 2026)
  2. yourEra: homepage (read Oct 26, 2026)
  3. EverPrime: Sermorelin page (read Oct 31, 2026)
  4. Embody: homepage (read Oct 26, 2026)
  5. Eden: homepage (read Oct 26, 2026)
  6. RxSpan MD: Longevity page (read Oct 26, 2026)

Strut Health

Top pick ·  8.6/10 ·  From $99/mo

Check eligibility with Strut Health (opens in a new tab)