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RxSpan MD longevity review

RxSpan MD prices each longevity treatment as a plan that includes the consult, medication, supplies and shipping. Sermorelin under-the-tongue tablets cost $142 a month on a prepaid 12-month plan or $179 month to month, and NAD+ injections $150 a month on 12 months or $249 month to month. It also offers NAD+ nasal spray, glutathione ($149 a month), MIC B12 and methylene blue ($99 a month).

  • Safety: Methylene blue carries a boxed warning for serotonin syndrome when taken with serotonergic drugs. Read before you start

By the RxLineup editorial team · Fact-checked against provider sites and FDA labels · Updated

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure
RxSpan MD logo

Rated 8.0 out of 10, Good

How we score

From $142/mo Sermorelin under-the-tongue tablets a month on a prepaid 12-month plan ($179 month to month), with the consult, medication, supplies and shipping included Billed $1,704 for 12 months

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

Check eligibility with RxSpan MD (opens in a new tab)

on rxspanmd.com

Treatments
6, listed below
Membership
None

What we like and what to watch

Strengths

  • Consult, medication and shipping in one plan price
  • Unlimited appointments and messaging
  • Free expedited delivery
  • LegitScript certified

Drawbacks

  • Lowest prices need a prepaid 12-month plan
  • NAD+ injections $249/mo month to month
  • Refund terms and pharmacy not published
  • States served not published

Best for

Lower monthly prices if you prepay for a year.

How RxSpan MD scores

Scored out of 10 on our five weighted criteria. The overall score, 8.0, is their weighted average. How we rate

  • Price & value 30%

  • Clinical care 25%

  • Medication options 20%

  • Transparency 15%

  • Experience 10%

What it costs

RxSpan MD pricing, checked Oct 26, 2026
Item Price
NAD+ injections Prepaid 12-month plan; $166 a month on 6 months, $199 on 3 months; consult, medication, supplies, shipping and support included $150/mo
Sermorelin Prepaid 12-month plan; $150 a month on 6 months, $166 on 3 months; consult, medication, supplies and shipping included $142/mo
Rapamycin Not offered
NAD+ nasal spray Prepaid 12-month plan; $158 a month on 6 months, $199 on 3 months, $249 month to month; consult, medication, supplies and shipping included $150/mo
Glutathione Month to month; consult, medication, supplies and shipping included $149/mo
Methylene blue Month to month; consult, medication, supplies and shipping included $99/mo
Vitamin B12 and lipotropic (MIC) injections Prepaid 12-month plan; $108 a month on 6 months, $116 on 3 months, $129 month to month; consult, medication, supplies and shipping included $100/mo
Membership No membership fee shown; each plan price includes the consult, medication, supplies, shipping and support None
Insurance No insurance billing listed; financing plans available –

– Not published by RxSpan MD.

How does that compare? See every provider’s price in our longevity price index.

Treatments offered

Small glass vial beside an off-white nasal spray bottle on warm limestone

Compounded products are prepared by licensed pharmacies and are not FDA-approved.

Safety

One of these treatments carries an FDA boxed warning, the strongest warning on a label: methylene blue.

Methylene blueCompounded; not FDA-approved
Boxed warning: serotonin syndrome with serotonergic drugs and opioids.
NAD+Compounded; not FDA-approved
There is no FDA label, and compounded NAD+ isn’t FDA-reviewed for safety, effectiveness or quality.
SermorelinCompounded; not FDA-approved
Compounded sermorelin isn’t FDA-reviewed for safety, effectiveness or quality, and its old Geref labeling covered children, not adults using it for aging.
GlutathioneCompounded; not FDA-approved
There is no FDA label for injectable glutathione, and compounded glutathione isn’t FDA-reviewed for safety, effectiveness or quality.
Vitamin B12 and lipotropic (MIC) injectionsCompounded; not FDA-approved
The cyanocobalamin label warns of anaphylaxis, which has been fatal, after injected B12; of low potassium when severe anemia is treated intensely; and of rapid optic nerve damage in people with early Leber’s disease.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

What’s included

  • Consult, medication, supplies, shipping and support in each plan price
  • Unlimited appointments and messaging with the care team
  • Monthly, 3-month, 6-month and 12-month prepaid plans, lower per month on longer plans
  • Free expedited delivery
  • Cancel or change plans anytime

How it works

Four steps, from the first questionnaire to refills.

Plain shipping box on a sunny front step

  1. Answer an online health questionnaire

    Your history, current medications and what you want to treat. It usually takes a few minutes.

  2. A licensed clinician reviews it

    If RxSpan MD needs more information, they’ll message you, ask for lab work or book a visit.

  3. Treatment ships to your door

    If you are prescribed, a licensed pharmacy ships your treatment.

  4. Refills and check-ins

    Your clinician renews or adjusts the prescription over time and answers your questions.

Is RxSpan MD legit?

What RxSpan MD’s own pages show, checked on Oct 26, 2026. LegitScript and a named pharmacy are checks on who prescribes and who fills; neither rates the care.

Who prescribes
Online intake; a licensed physician reviews and approves every plan. Unlimited appointments and messaging with the care team, 24/7. Founded by Dr. John Diaz, a board-certified plastic surgeon.
LegitScript
Displays LegitScript certification, a third-party check against licensing and pharmacy rules. It isn’t a rating of the care.
Pharmacy
Doesn’t name its pharmacy on its pages.
Prices
Publishes 8 prices before you sign up.
Refunds and terms
Refund terms and pharmacy not published.
Last checked
October 26, 2026, against 6 of its own pages.

The fine print

Prices
As listed on rxspanmd.com when we checked on Oct 26, 2026. The $142 starting price needs a commitment: 12-month plan, prepaid (billed $1,704 for 12 months). Prices change often and some are introductory, so confirm the total before you pay.
Refunds and guarantee
Refund terms and pharmacy not published
Availability
Not stated; check during intake.
LegitScript certified
Yes

Alternatives

Other highly rated longevity clinics, highest score first, and how they compare head to head.

  1. 01
    Strut Health

    Low-cost sermorelin, including a needle-free lozenge

    Rated 8.6 out of 10, Very good

    From $99/mo

    Visit site for Strut Health (opens in a new tab)
  2. 02
    yourEra

    Regular check-ins and a live visit whenever you want one

    Rated 8.5 out of 10, Very good

    From $170/mo

    Visit site for yourEra (opens in a new tab)
  3. 03
    EverPrime

    Sermorelin with IGF-1 labs every 6 months

    Rated 8.4 out of 10, Very good

    From $169/mo

    Visit site for EverPrime (opens in a new tab)
  4. 04
    Embody

    Sermorelin at one flat all-in monthly price, with the pharmacies named

    Rated 8.3 out of 10, Very good

    From $149/mo On sale now: $99/mo† † Sale price; regularly $149

    Visit site for Embody (opens in a new tab)

Guides to read before you choose

More on longevity

Questions, answered

Is RxSpan MD legit?
RxSpan MD shows LegitScript’s certification seal for rxspanmd.com. A licensed physician reviews each case and approves the plan, and licensed pharmacies fill prescriptions; RxSpan MD doesn’t name them. Its founder is Dr. John Diaz, a board-certified plastic surgeon. No NAD+, sermorelin or glutathione product is FDA-approved.

How much does RxSpan MD cost?
As of October 2026, sermorelin tablets cost $179 a month month to month, $166 on a 3-month plan, $150 on 6 months and $142 on 12 months, prepaid. NAD+ injections cost $249, $199, $166 and $150 a month on the same plans. Glutathione is $149 a month, MIC B12 from $100 and methylene blue $99. Each price includes the consult, medication, supplies and shipping.

Does RxSpan MD take insurance?
Its pages don’t say it bills insurance. It offers financing plans. For longevity, RxSpan MD’s published price is from $142/mo, billed $1,704 for 12 months.

What does RxSpan MD prescribe for longevity?
RxSpan MD offers NAD+ injections, NAD+ nasal spray, sermorelin, glutathione, methylene blue and vitamin B12 and lipotropic injections. A licensed clinician decides whether a treatment is right for you. Compounded products are not FDA-approved.

Can I cancel RxSpan MD?
Refund terms and pharmacy not published. We last checked RxSpan MD’s longevity pages on October 26, 2026.

Sources (checked Oct 26, 2026)

  1. RxSpan MD: homepage
  2. RxSpan MD: Longevity page
  3. RxSpan MD: Products page
  4. RxSpan MD: About page
  5. RxSpan MD: Terms of service page
  6. LegitScript: certification check for rxspanmd.com

RxSpan MD

8.0/10 ·  From $142/mo, 12 mo prepaid

Check eligibility with RxSpan MD (opens in a new tab)