How much does semaglutide cost in 2026?

Semaglutide costs $349 a month self-pay as the Wegovy or Ozempic pen at most doses, as of November 6, 2026, with $199 for a new patient’s first two fills. As a daily pill it costs $149 to $299 a month by dose, and compounded semaglutide runs $75.58 to $299 a month at the programs we rank. Insurance with Novo’s savings offer can bring a brand-name fill to $25, and eligible Medicare enrollees pay $50 for Wegovy.

Brand prices below come from Novo Nordisk’s NovoCare pages and price guide, read on November 6, 2026; Novo can change or end its offers at any time. Program prices come from each program’s own site, as of November 2026. Both pens are taken once a week and both pills once a day. NovoCare’s “month” is a box of 4 Wegovy pens, 1 Ozempic pen or a bottle of 30 tablets.

Semaglutide cost at a glance

Wegovy and Ozempic pen prices by dose

On its label, Wegovy starts at 0.25 mg a week for 4 weeks and steps up every 4 weeks to the usual 2.4 mg maintenance dose. Ozempic starts the same way and can go to 1 mg or 2 mg if blood sugar needs more control.

The $199 price is for patients new to Novo’s savings offer or NovoCare home delivery, covers two monthly fills and runs through December 31, 2026. Novo lists the Wegovy pen at $1,349.02 a package and Ozempic at $1,027.51 a pen, but those are list prices before discounts, not what a cash buyer on the self-pay offer pays. Our Wegovy cost and Ozempic cost guides go through each brand in full.

The Wegovy pill and Ozempic pill

The Wegovy pill is a daily semaglutide tablet approved for weight loss. On its label you take 1.5 mg for 30 days, then 4 mg, then 9 mg, and 25 mg from day 91, on an empty stomach with up to 4 ounces of water. On a limited-time offer, NovoCare charges $149 at 1.5 mg, $199 at 4 mg and $299 at 9 mg and 25 mg, so the first 12 bottles come to $3,338. In its trial, the 25 mg dose produced 13.6% average weight loss over 64 weeks.

The Ozempic pill is the diabetes tablet, at $149 for 1.5 mg, $199 for 4 mg and $299 for 9 mg self-pay. Our Wegovy pill cost guide has the details.

Compounded semaglutide prices

Taking each program’s lowest ongoing monthly price, with medication and any required membership included, compounded semaglutide runs $75.58 to $299 a month at the programs we rank, as of November 2026. The median is $161.42. That counts prepaid plans of any length and leaves out first-month and sale prices. A sample, from the cheapest up:

The low end usually needs a commitment: Belle’s $93 and HealthRX’s $104.99 need a year, and Collective’s $75.58 includes a membership billed once a year. Where a program doesn’t publish dose pricing, ask for the price at your likely maintenance dose before you pay.

The lower price buys a different product. Compounded semaglutide is not Wegovy or Ozempic, and not a generic of either. A compounding pharmacy prepares it, it isn’t FDA-approved, and the FDA says compounded drugs “are not reviewed by the agency for safety, effectiveness or quality prior to marketing” (FDA). The FDA also warns that some compounders have used semaglutide salt forms, such as semaglutide sodium, which are different active ingredients from the approved drugs (FDA). Our guide to whether compounded semaglutide is legal and safe covers the rules.

Compare them on our compounded semaglutide rankings, ordered by our published score, or see every program’s price in the weight-loss price index.

What online programs charge for Wegovy and Ozempic

Some programs pass on Novo’s self-pay price and add a membership; others charge far more. As of November 2026:

Ask which pharmacy fills the prescription and what you’ll pay at your dose. Our semaglutide provider rankings list the programs that prescribe it, brand and compounded.

Semaglutide cost with insurance or Medicare

• Commercial insurance that covers it: Novo’s offer lets you pay as little as $25, with savings capped at $100 a month. Government beneficiaries are excluded. The Ozempic offer needs a prescription “for an FDA-approved indication,” so it doesn’t apply to weight loss alone.
• Commercial insurance that doesn’t cover it: you can use the self-pay prices above, outside your insurance.
• Medicare Part D: the Medicare GLP-1 Bridge charges eligible enrollees a $50 copay from July 1, 2026 to December 31, 2027. Its form lists the Wegovy injection, Wegovy tablets and Wegovy HD, not Ozempic. The $50 doesn’t count toward your Part D out-of-pocket costs.
• Medicare from 2027: CMS negotiated a price of $274 for a 30-day supply of Ozempic, Rybelsus and Wegovy from January 1, 2027, against a $959 list price in 2024 (CMS). That is what Part D plans pay, not your copay.

Our guide to GLP-1s without insurance covers cash options across brands, and our Costco GLP-1 prices guide covers warehouse pharmacy prices.

What a year of semaglutide costs

A box of 4 Wegovy pens or 1 Ozempic pen covers 28 days, so a year takes 13 fills. These are medication totals, plus the program fee where a compounded price includes one.

The bottom line

As of November 6, 2026, semaglutide costs $349 a month as a self-pay Wegovy or Ozempic pen at most doses, $399 as Wegovy HD, $149 to $299 as a pill, and $75.58 to $299 a month as a compounded plan, which isn’t FDA-approved. Coverage with Novo’s offer can bring a fill to $25, and Medicare’s Bridge charges $50 for Wegovy. Check your coverage first, then talk to a licensed clinician about which form and dose suit you. For the whole field, start from our weight-loss hub or our guide to the best weight loss medications.