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Sesame review

Sesame lets you pick your own provider, and its Success by Sesame subscription covers video visits, unlimited messaging and Quest labs for $99 a month, or $59 on the annual plan. Medication is billed separately at published cash prices, from $149 a month for the Wegovy pill or Foundayo and $299 for Zepbound, or through insurance with prior authorization help.

By the RxLineup editorial team · Fact-checked against provider sites and FDA labels · Updated

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure
Sesame logo

Rated 8.0 out of 10, Good

How we score

From $248/mo Wegovy pill: $149 + $99/mo membership

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

Check eligibility with Sesame (opens in a new tab)

on sesamecare.com

Medications
Wegovy pill, Wegovy, Ozempic, Zepbound, Foundayo
Insurance
Helps with claims
Same price at every dose
No

What we like and what to watch

Strengths

  • Pick your own provider; video visits included
  • Labs at Quest included in most states
  • Help with prior authorization for insured medication
  • Dose-by-dose cash prices published

Drawbacks

  • Medication billed on top of the subscription
  • No refund for the first month once the first visit has happened
  • Month-to-month plan charged every 28 days, per its billing FAQ
  • No compounded options
  • Quest labs not included in nine states

Best for

Choosing your own provider, with video visits and labs.

How Sesame scores

Scored out of 10 on our five weighted criteria. The overall score, 8.0, is their weighted average. How we rate

  • Price & value 30%

  • Clinical care 25%

  • Medication options 20%

  • Transparency 15%

  • Experience 10%

What it costs

Sesame pricing, checked Oct 26, 2026
Item Price
Zepbound LillyDirect self-pay price, billed by the pharmacy on top of the membership. 2.5 mg $299, 5 mg $399, then $449 for 7.5 mg and up if you refill within 45 days ($499 to $699 otherwise). $299–$449/mo
Wegovy NovoCare Pharmacy self-pay price, billed by the pharmacy on top of the membership. $199 for the first two fills (0.25 mg and 0.5 mg, new patients, through Dec 31, 2026), then $349 at every dose up to 2.4 mg. $199–$349/mo
Wegovy pill NovoCare Pharmacy self-pay price, billed by the pharmacy on top of the membership. 1.5 mg $149, 4 mg $199, then $299 for 9 mg and 25 mg. Labeled a limited-time offer. $149–$299/mo
Foundayo LillyDirect self-pay price, billed by the pharmacy on top of the membership. 0.8 mg and 2.5 mg $149, 5.5 mg $199, then $299 for 9 mg and up. Some prices are reduced through Dec 31, 2026. $149–$299/mo
Membership Success by Sesame: $99/month month to month (its billing FAQ says this plan is charged every 28 days), or $59/month on the annual plan; 3- and 6-month plans save $60 and $180 per term. Includes video visits, unlimited messaging and labs at Quest (except in AZ, HI, ND, NJ, NY, OK, RI, SD and WY). Medication is not included. Sesame notes that providers set their own prices, so some charge more $99/mo
Insurance The subscription is self-pay, with an itemized bill for HSA/FSA on request. Insurance can cover weight-loss medication (as low as $25/month), and your provider helps with prior authorization Helps with claims

Want a full estimate with membership and dose changes? Try the GLP-1 cost calculator.

Medications offered

Unbranded injection pen on a warm limestone surface

Safety

One of these treatments carries an FDA boxed warning, the strongest warning on a label: GLP-1 medications.

Wegovy pillFDA-approved for long-term weight reduction (adults)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
WegovyFDA-approved for long-term weight reduction (adults, and children 12 and older)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
OzempicFDA-approved drug; used off-label here
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
ZepboundFDA-approved for long-term weight reduction (adults)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
FoundayoFDA-approved for long-term weight reduction (adults)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

What’s included

  • Choose your own provider and meet by video
  • Labs at Quest included in most states
  • Unlimited messaging with your provider
  • Same-day pharmacy pickup or home delivery
  • Help with prior authorization for covered medication

How it works

Four steps, from the first questionnaire to ongoing dose changes.

Plain shipping box on a sunny front step

  1. Answer an online health questionnaire

    Your history, current medications and goals. It usually takes a few minutes.

  2. A licensed clinician reviews it

    If Sesame needs more information, they’ll message you or book a visit.

  3. Medication ships to your door

    If you are prescribed, a licensed pharmacy ships your medication and supplies.

  4. Ongoing check-ins and dose changes

    Your clinician adjusts your dose over time and helps with side effects.

Is Sesame legit?

What Sesame’s own pages show, checked on Oct 26, 2026. LegitScript and a named pharmacy are checks on who prescribes and who fills; neither rates the care.

Who prescribes
Pick your own Sesame provider; video consultation; labs ordered if needed; unlimited messaging; prescription to local pharmacy same-day or home delivery.
LegitScript
Displays LegitScript certification, a third-party check against licensing and pharmacy rules. It isn’t a rating of the care.
Pharmacy
Sends prescriptions to a pharmacy you choose.
Prices
Publishes 7 prices before you sign up.
Refunds and terms
Full refund if you cancel at least 3 hours before your first visit.
Last checked
October 26, 2026, against 4 of its own pages.

The fine print

Prices
As listed on sesamecare.com when we checked on Oct 26, 2026. Prices change often and some are introductory, so confirm the total before you pay.
Refunds and guarantee
Full refund if you cancel at least 3 hours before your first visit.
Availability
Not stated; check during intake.
LegitScript certified
Yes

Alternatives

Other highly rated programs, highest score first, and how each compares head to head.

  1. 01
    Eden

    A flat all-in price with a results warranty

    Rated 9.1 out of 10, Excellent

    From $99/mo

    Visit site for Eden (opens in a new tab)
  2. 02
    Measured

    Low compounded prices, plus prior authorization help for brand-name GLP-1s

    Rated 9.0 out of 10, Excellent

    From $199/mo

    Visit site for Measured (opens in a new tab)
  3. 03
    MEDGm

    Labs and video access included, with tablets and brand-name options

    Rated 9.0 out of 10, Excellent

    From $299/mo

    Visit site for MEDGm (opens in a new tab)
  4. 04
    Gala GLP-1

    Coaching and app support at a low flat price

    Rated 8.8 out of 10, Excellent

    From $129/mo

    Visit site for Gala GLP-1 (opens in a new tab)

Guides to read before you choose

More on weight loss

Questions, answered

Is Sesame legit for weight loss?
Sesame links to its LegitScript approval from its weight-loss page. You choose a licensed Sesame provider, meet by video, and labs are ordered if needed before a prescription.

How much does Success by Sesame cost?
The subscription is $99 a month month to month or $59 a month on the annual plan, with savings on 3- and 6-month plans. Medication is extra: cash prices start at $149 a month for the Wegovy pill (1.5 mg and 4 mg) and Foundayo, $199 for the first two months of Wegovy or Ozempic, and $299 for Zepbound at 2.5 mg.

Does Sesame take insurance?
For the medication, yes: Sesame says it can cost as little as $25 a month with insurance, and your provider helps with prior authorization. The subscription itself is self-pay, with an itemized bill for HSA or FSA on request.

What GLP-1 medications does Sesame prescribe?
Sesame offers Wegovy pill, Wegovy, Ozempic, Zepbound, Foundayo. A licensed clinician decides whether a medication is appropriate for you.

Can I cancel Sesame?
No refund for the first month once the first visit has happened Full refund if you cancel at least 3 hours before your first visit.

Sources (checked Oct 26, 2026)

  1. Sesame: Online weight loss program page
  2. Sesame: Wegovy page
  3. Sesame: Zepbound page
  4. Sesame: Wegovy pill page

Sesame

8.0/10 ·  From $248/mo

Check eligibility with Sesame (opens in a new tab)