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RxSpan MD weight loss review

RxSpan MD prescribes compounded semaglutide and tirzepatide as weekly injections or daily capsules, plus brand-name Ozempic, Wegovy and Zepbound. Plan prices include the consult, medication, shipping and support: semaglutide is $249 a month, or $219 and $199 a month on 3- and 6-month plans paid up front, and tirzepatide injections start at $329 a month.

By the RxLineup editorial team · Fact-checked against provider sites and FDA labels · Updated

· How we rate

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We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure
RxSpan MD logo

Rated 7.9 out of 10, Good

How we score

From $249/mo Compounded semaglutide injection or capsules, monthly plan, with consult, medication, supplies, shipping and support included

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

Check eligibility with RxSpan MD (opens in a new tab)

on rxspanmd.com

Medications
Sema, Tirz, Oral GLP-1, Ozempic, Wegovy, Zepbound
Same price at every dose
Not stated

What we like and what to watch

Strengths

  • Compounded semaglutide and tirzepatide as injections or capsules
  • Brand-name Ozempic, Wegovy and Zepbound also available
  • Consult, medication and shipping in one price
  • Unlimited appointments and 24/7 messaging; LegitScript seal

Drawbacks

  • $249/month semaglutide month to month, above most programs we track
  • No refund or cancellation terms published
  • Product cards label each price “for the first month”, though the plan box shows the same monthly price
  • Dose pricing and a state list not published

Best for

Compounded GLP-1 capsules or brand-name pens in one physician-led program.

How RxSpan MD scores

Scored out of 10 on our five weighted criteria. The overall score, 7.9, is their weighted average. How we rate

  • Price & value 30%

  • Clinical care 25%

  • Medication options 20%

  • Transparency 15%

  • Experience 10%

What it costs

RxSpan MD pricing, checked Oct 26, 2026
Item Price
Starting price Compounded semaglutide injection or capsules, monthly plan, with consult, medication, supplies, shipping and support included $249/mo
Compounded semaglutide Billed $2,094 for 12 months. $175/mo
Compounded tirzepatide Billed $1,734 for 6 months. $289/mo
Membership No separate membership. Plan prices include the consult, medication, supplies, shipping and support, prepaid monthly or for 3, 6 or 12 months None
Insurance Insurance isn’t mentioned; plans are prepaid, with CareCredit financing offered –

– Not published by RxSpan MD.

Want a full estimate with membership and dose changes? Try the GLP-1 cost calculator.

Medications offered

Unbranded injection pen on a warm limestone surface

Compounded medications are prepared by licensed pharmacies and are not FDA-approved.

Safety

One of these treatments carries an FDA boxed warning, the strongest warning on a label: GLP-1 medications.

SemaglutideNot FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2. FDA label
TirzepatideNot FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2. FDA label
Compounded GLP-1sCompounded; not FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
OzempicFDA-approved drug; used off-label here
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
WegovyFDA-approved for long-term weight reduction (adults, and children 12 and older)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
ZepboundFDA-approved for long-term weight reduction (adults)
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

What’s included

  • Compounded semaglutide or tirzepatide as a weekly injection or a daily capsule
  • Brand-name Ozempic, Wegovy and Zepbound
  • Unlimited appointments and 24/7 messaging with the care team
  • Free expedited delivery
  • CareCredit financing

How it works

Four steps, from the first questionnaire to ongoing dose changes.

Plain shipping box on a sunny front step

  1. Answer an online health questionnaire

    Your history, current medications and goals. It usually takes a few minutes.

  2. A licensed clinician reviews it

    If RxSpan MD needs more information, they’ll message you or book a visit.

  3. Medication ships to your door

    If you are prescribed, a licensed pharmacy ships your medication and supplies.

  4. Ongoing check-ins and dose changes

    Your clinician adjusts your dose over time and helps with side effects.

Is RxSpan MD legit?

What RxSpan MD’s own pages show, checked on Oct 26, 2026. LegitScript and a named pharmacy are checks on who prescribes and who fills; neither rates the care.

Who prescribes
Online intake; a licensed physician reviews and approves every plan. Unlimited appointments and messaging with the care team, 24/7. Founded by Dr. John Diaz, a board-certified plastic surgeon.
LegitScript
Displays LegitScript certification, a third-party check against licensing and pharmacy rules. It isn’t a rating of the care.
Pharmacy
Doesn’t name its pharmacy on its pages.
Prices
Publishes 12 prices before you sign up.
Refunds and terms
No refund or cancellation terms published.
Last checked
October 26, 2026, against 6 of its own pages.

The fine print

† Prices
As listed on rxspanmd.com when we checked on Oct 26, 2026. The $175/mo price for compounded semaglutide is a sale price (regular price not published). Prices change often and some are introductory, so confirm the total before you pay.
Refunds and guarantee
No refund or cancellation terms published
Availability
Not stated; check during intake.
LegitScript certified
Yes

Alternatives

Other highly rated programs, highest score first, and how each compares head to head.

  1. 01
    Eden

    A flat all-in price with a results warranty

    Rated 9.1 out of 10, Excellent

    From $99/mo

    Visit site for Eden (opens in a new tab)
  2. 02
    Measured

    Low compounded prices, plus prior authorization help for brand-name GLP-1s

    Rated 9.0 out of 10, Excellent

    From $199/mo

    Visit site for Measured (opens in a new tab)
  3. 03
    MEDGm

    Labs and video access included, with tablets and brand-name options

    Rated 9.0 out of 10, Excellent

    From $299/mo

    Visit site for MEDGm (opens in a new tab)
  4. 04
    Gala GLP-1

    Coaching and app support at a low flat price

    Rated 8.8 out of 10, Excellent

    From $129/mo

    Visit site for Gala GLP-1 (opens in a new tab)

Guides to read before you choose

More on weight loss

Questions, answered

Is RxSpan MD legit?
RxSpan MD shows a LegitScript seal on its site. It was founded by Dr. John Diaz, a board-certified plastic surgeon, and a licensed physician reviews every plan before a prescription. Medication is filled by licensed U.S. pharmacies it doesn’t name.

How much does RxSpan MD cost?
Compounded semaglutide, as an injection or capsules, is $249 a month, $219 a month on a 3-month plan and $199 a month on a 6-month plan. Tirzepatide injections are $329, $309 and $289 a month, and tirzepatide capsules $349, $299 and $289. A 12-month plan is shown only with the STARTNOW promo applied. Ozempic is $1,299, Wegovy $1,349 and Zepbound $1,069 a month. Prices include the consult, supplies, shipping and support.

Does RxSpan MD offer oral GLP-1s?
Yes: compounded semaglutide and tirzepatide capsules, taken daily. They are not the Wegovy pill or any other approved drug. A compounding pharmacy prepares them, and they aren’t FDA-approved. RxSpan MD itself notes there is no FDA-approved oral tirzepatide.

Does RxSpan MD take insurance?
Insurance isn’t mentioned; plans are prepaid, with CareCredit financing offered.

Can I cancel RxSpan MD?
No refund or cancellation terms published. We last checked RxSpan MD’s weight loss pages on October 26, 2026.

Sources (checked Oct 26, 2026)

  1. RxSpan MD: homepage
  2. RxSpan MD: Main weight loss page
  3. RxSpan MD: Weight loss page
  4. RxSpan MD: Products page
  5. RxSpan MD: About page
  6. RxSpan MD: Terms of service page

RxSpan MD

7.9/10 ·  From $249/mo

Check eligibility with RxSpan MD (opens in a new tab)