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DudeMeds weight loss review

DudeMeds sells compounded semaglutide and tirzepatide (each with vitamin B6) as one-time 8-week supplies with no automatic renewal, and lists the price at every dose: semaglutide is $392 to $552 per 8 weeks (about $212 to $299 a month) and tirzepatide $472 to $792 (about $256 to $429). New patients can start with a 4-week intro supply for $99 or $149. The offers aren’t available in Alabama, Arkansas, California, Kentucky or South Carolina.

By the RxLineup editorial team · Fact-checked against provider sites and FDA labels · Updated

· How we rate

Advertiser disclosure

RxLineup earns a fee when you click a link to a provider and complete a qualifying step. Only providers that pay us appear in our rankings and reviews. Our guides also name providers that don’t pay us, so you can see the whole market.

We don’t cover every program on the market. Prices change often, so confirm the details with the provider before you enroll.

Full disclosure
DudeMeds logo

Rated 7.7 out of 10, Good

How we score

From $212/mo Compounded semaglutide + B6, $392 per 8-week supply (1 mg a week, or the new-patient Kickstart at 0.25 to 0.5 mg), about $212.33 a calendar month; the $99 first 4 weeks is an intro offer

Only providers that pay us appear in our rankings and reviews, and we’re paid when you sign up through our links. How we make money

Check eligibility with DudeMeds (opens in a new tab)

on dudemeds.com

Medications
Sema, Tirz
Same price at every dose
No

What we like and what to watch

Strengths

  • Price published for every dose step
  • No subscription or automatic renewal
  • New-patient intro: semaglutide $99, tirzepatide $149 for 4 weeks
  • LegitScript seal on the site

Drawbacks

  • Ongoing cost from about $212/month, above most programs we track
  • Price rises with dose, to $552 (semaglutide) or $792 (tirzepatide) per 8 weeks
  • Compounded medication only; no brand-name option
  • Not available in AL, AR, CA, KY or SC

Best for

Seeing the price of every dose step, with no subscription.

How DudeMeds scores

Scored out of 10 on our five weighted criteria. The overall score, 7.7, is their weighted average. How we rate

  • Price & value 30%

  • Clinical care 25%

  • Medication options 20%

  • Transparency 15%

  • Experience 10%

What it costs

DudeMeds pricing, checked Oct 26, 2026
Item Price
Starting price Compounded semaglutide + B6, $392 per 8-week supply (1 mg a week, or the new-patient Kickstart at 0.25 to 0.5 mg), about $212.33 a calendar month; the $99 first 4 weeks is an intro offer $212/mo
Compounded semaglutide $107/mo
Compounded tirzepatide $161/mo
Membership No membership or subscription. Each GLP-1 offer is a one-time purchase of a 4- or 8-week supply, with no automatic renewal; returning patients request the next supply in the patient portal None
Insurance Insurance isn’t mentioned; each supply is a one-time cash purchase –
Six months, all-in Semaglutide; from $969 for tirzepatide. Can be higher as your dose rises. From $644

– Not published by DudeMeds.

Want a full estimate with membership and dose changes? Try the GLP-1 cost calculator.

Medications offered

Small unlabeled glass vial on a warm limestone surface

Compounded medications are prepared by licensed pharmacies and are not FDA-approved.

Safety

One of these treatments carries an FDA boxed warning, the strongest warning on a label: GLP-1 medications.

SemaglutideNot FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2. FDA label
TirzepatideNot FDA-approved
GLP-1 medications carry a boxed warning for thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2. FDA label

Not medical advice. A licensed clinician decides whether a treatment is right for you; read the full prescribing information before you start.

What’s included

  • No subscription or automatic renewal
  • Provider review in the patient portal, with labs or a video visit if the provider asks
  • Semaglutide and tirzepatide compounded with vitamin B6

How it works

Four steps, from the first questionnaire to ongoing dose changes.

Plain shipping box on a sunny front step

  1. Answer an online health questionnaire

    Your history, current medications and goals. It usually takes a few minutes.

  2. A licensed clinician reviews it

    If DudeMeds needs more information, they’ll message you or book a visit.

  3. Medication ships to your door

    If you are prescribed, a licensed pharmacy ships your medication and supplies.

  4. Ongoing check-ins and dose changes

    Your clinician adjusts your dose over time and helps with side effects.

Is DudeMeds legit?

What DudeMeds’s own pages show, checked on Oct 26, 2026. LegitScript and a named pharmacy are checks on who prescribes and who fills; neither rates the care.

Who prescribes
ED and hair treatments: online questionnaire reviewed by a U.S.-licensed provider. Testosterone, enclomiphene and the TRT combo: a live video visit and lab work, with a 16-biomarker core TRT lab panel included in the plan. Follow-up runs through the patient portal, and the provider may ask for more tests or a visit.
LegitScript
Displays LegitScript certification, a third-party check against licensing and pharmacy rules. It isn’t a rating of the care.
Pharmacy
Doesn’t name its pharmacy on its pages.
Prices
Publishes 8 prices before you sign up.
Refunds and terms
No refund terms stated.
Last checked
October 26, 2026, against 6 of its own pages.

The fine print

† Prices
As listed on dudemeds.com when we checked on Oct 26, 2026. The $107/mo price for compounded semaglutide is a sale price (regular price not published). The $161/mo price for compounded tirzepatide is a sale price (regular price not published). Prices change often and some are introductory, so confirm the total before you pay.
Refunds and guarantee
No guarantee stated on the pages we reviewed.
Availability
Not stated; check during intake.
LegitScript certified
Yes

Alternatives

Other highly rated programs, highest score first, and how each compares head to head.

  1. 01
    Eden

    A flat all-in price with a results warranty

    Rated 9.1 out of 10, Excellent

    From $99/mo

    Visit site for Eden (opens in a new tab)
  2. 02
    Measured

    Low compounded prices, plus prior authorization help for brand-name GLP-1s

    Rated 9.0 out of 10, Excellent

    From $199/mo

    Visit site for Measured (opens in a new tab)
  3. 03
    MEDGm

    Labs and video access included, with tablets and brand-name options

    Rated 9.0 out of 10, Excellent

    From $299/mo

    Visit site for MEDGm (opens in a new tab)
  4. 04
    Gala GLP-1

    Coaching and app support at a low flat price

    Rated 8.8 out of 10, Excellent

    From $129/mo

    Visit site for Gala GLP-1 (opens in a new tab)

Guides to read before you choose

More on weight loss

Questions, answered

Is DudeMeds legit?
DudeMeds shows a LegitScript seal on its site. A U.S.-licensed provider reviews your secure intake and decides whether treatment is appropriate, and may ask for tests or a video visit first.

How much does DudeMeds cost for GLP-1s?
New patients can buy a 4-week intro supply: semaglutide + B6 for $99 or tirzepatide + B6 for $149. After that, 8-week supplies cost $392, $472 or $552 for semaglutide (1, 1.5 or 2 mg a week) and $472, $600 or $792 for tirzepatide (5, 7.5 or 10 mg a week). Each is a one-time total, if prescribed.

Is DudeMeds a subscription?
Not for its GLP-1 offers. Each is a one-time purchase with no automatic renewal; returning patients request the next supply in their patient portal, subject to provider review. Compounded semaglutide and tirzepatide are not Wegovy or Zepbound, and not generics of them. A compounding pharmacy prepares them, and they aren’t FDA-approved.

Does DudeMeds take insurance?
Insurance isn’t mentioned on its weight-care pages; each supply is a one-time cash purchase.

What GLP-1 medications does DudeMeds prescribe?
DudeMeds offers Semaglutide (compounded), Tirzepatide (compounded). A licensed clinician decides whether a medication is appropriate for you. Compounded medications are not FDA-approved.

Can I cancel DudeMeds?
Check the cancellation terms before you pay. We last checked DudeMeds’s weight loss pages on October 26, 2026.

Sources (checked Oct 26, 2026)

  1. DudeMeds: Weight loss page
  2. DudeMeds: Semaglutide page
  3. DudeMeds: Tirzepatide page
  4. DudeMeds: Sema kickstart page
  5. DudeMeds: How it works page
  6. DudeMeds: Terms of sale page

DudeMeds

7.7/10 ·  From $212/mo

Check eligibility with DudeMeds (opens in a new tab)