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Normal testosterone levels by age

What counts as normal, how testosterone changes after 40, and the cut-offs clinicians use before they prescribe.

By the RxLineup editorial team · Fact-checked against provider sites and FDA labels · Updated  · 6 min read

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In short

  1. In healthy nonobese men aged 19 to 39, the harmonized normal range for total testosterone is 264 to 916 ng/dL, with a median of 531 ng/dL (Travison et al., 2017).
  2. In the Massachusetts Male Aging Study, total testosterone fell 1.6% a year within the same men aged 40 to 70, and free and bioavailable testosterone 2% to 3% a year.
  3. The American Urological Association uses a total testosterone below 300 ng/dL as a reasonable cut-off for low testosterone, together with symptoms.
  4. Testosterone labels require two morning tests on separate days below the normal range before treatment, and the Endocrine Society recommends fasting morning samples.
  5. FDA labels still say safety and efficacy in age-related hypogonadism haven’t been established, so a low number alone isn’t the whole decision.

A normal total testosterone level for a healthy young man is roughly 264 to 916 ng/dL, according to the largest effort to standardize the measurement across labs. Levels then drift down slowly with age, by about 1% to 2% a year in men over 40. Clinicians usually start to consider low testosterone below 300 ng/dL, but only with symptoms and only after repeat morning tests. Here is what the numbers mean, and why a single result rarely settles the question.

The normal range, and where it comes from

Testosterone assays used to disagree from lab to lab. In 2017, researchers working with the CDC measured samples from four large cohorts, 9,054 community-dwelling men in the United States and Europe, against a reference method, then converted every cohort to the same scale (Travison et al.). For healthy nonobese men aged 19 to 39, the harmonized percentiles were:

PercentileTotal testosterone (ng/dL)
2.5th264
5th303
50th (median)531
95th852
97.5th916

The authors call 264 to 916 ng/dL the harmonized normal range for that group. They also found that age-specific levels in nonobese men were higher than in all men, so body weight shifts the numbers too. Your lab may print a slightly different range, because each lab sets its own. Read your result against the range on your report.

How testosterone changes with age

The best long-term data come from the Massachusetts Male Aging Study, which tested 1,709 men aged 40 to 70 in 1987 to 1989 and followed 1,156 of them for 7 to 10 years. It measured the decline two ways:

MeasureDecline per year
Total testosterone, comparing men of different ages0.8%
Total testosterone, within the same men over time1.6%
Free and albumin-bound testosterone, comparing men of different agesAbout 2%
Bioavailable testosterone, within the same men over time2% to 3%

Sex hormone-binding globulin (SHBG), the protein that carries testosterone in the blood, rose about 1.6% a year across age groups, while free testosterone fell faster than total testosterone.

Health mattered. Men without chronic illness, prescription medicines, obesity or heavy drinking had levels of several androgens 10% to 15% higher. The decline within men was steeper than the difference between age groups, which the authors read as a sign that new illness may speed up the drop.

What this means in practice: the harmonized study derived age-specific values, but its headline normal range is the one for men aged 19 to 39, and labs print their own reference ranges. Ask whether your lab’s range is adjusted for age, and track your own results over time rather than comparing them with a single chart.

Total vs free testosterone

Most tests report total testosterone: the hormone bound to SHBG, the hormone loosely bound to albumin, and the small free fraction together. Free and albumin-bound testosterone are the parts tissues can use, which is why some reports also show “bioavailable” or free testosterone.

Total testosterone is the starting point. The Endocrine Society recommends measuring free testosterone when total testosterone is near the lower limit of normal, or when a condition changes SHBG, using equilibrium dialysis or an accurate formula. In the Massachusetts study, free testosterone fell faster with age than total testosterone, so an older man with a borderline total can have a clearly low free level. Ask your clinician which number your plan is based on.

What else moves the number

Age is only one factor. In the Massachusetts study, men without chronic illness, prescription medicines, obesity or heavy drinking had androgen levels 10% to 15% higher, and the harmonized study found higher levels in nonobese men than in men overall. The Endocrine Society recommends looking for the cause once low testosterone is confirmed, because treating that cause can matter as much as the number. If your result is low, expect questions about your weight, sleep, medicines and other conditions before any prescription.

The cut-offs clinicians use

Below 300 ng/dL

The AUA guideline uses a total testosterone below 300 ng/dL as a reasonable cut-off for diagnosing low testosterone, alongside symptoms and signs. TRAVERSE, the largest heart-safety trial of testosterone, enrolled men with two fasting levels below 300 ng/dL and adjusted doses to keep them between 350 and 750 ng/dL (Lincoff et al.).

Two morning tests

FDA labels set a firm rule before any prescription. The Depo-Testosterone label says to confirm hypogonadism with serum testosterone measured in the morning on at least two separate days, with both results below the normal range. The Endocrine Society guideline adds fasting, an accurate assay and a repeat test to confirm. When total testosterone is near the lower limit, or SHBG is likely to be abnormal, it recommends measuring free testosterone too.

Normal ranges in drug trials

Each FDA label defines “normal” for its own study, using its own assay. The numbers below aren’t comparable with each other or with your lab report, but they show why a single cut-off doesn’t exist:

ProductNormal range used in its label study
AndroGel 1.62%300 to 1,000 ng/dL
Kyzatrex222 to 800 ng/dL
Tlando300 to 1,080 ng/dL
Xyosted300 to 1,100 ng/dL

Every testosterone label we checked, including Depo-Testosterone, AndroGel 1.62%, Kyzatrex and Jatenzo, still states that safety and efficacy in men with “age-related hypogonadism” have not been established. In plain terms, the FDA approved testosterone for men whose low levels have a medical cause, such as testicular failure or a pituitary problem, and hasn’t approved it for the gradual decline that comes with age. Clinicians can still prescribe it, but it is a judgment call to discuss with yours, weighing your symptoms, your numbers and your risks.

Some online clinics set their own age limits. Henry Meds, for example, treats men aged 35 to 65 whose lab results meet its criteria.

Getting your level tested

If you want a number, get a morning blood test, ideally fasting, and repeat it if it comes back low. Several online clinics start with one: Hims mails a lab kit, Hone Health offers an at-home or partner-lab test for $65 with a physician consult, and Rex MD sends you to Labcorp or Quest for $99 with a video visit, as of October 2026. See clinics with at-home tests and how to get TRT online.

Bring your symptoms to the conversation. The Endocrine Society recommends diagnosing low testosterone only in men with symptoms and signs and consistently low levels, so a low number with no symptoms, or symptoms with a normal number, usually calls for more testing rather than a prescription.

If your level is low

Treatment options include testosterone injections, gels and creams, oral capsules and, for some men with secondary hypogonadism, enclomiphene, which raises your own production. Testosterone is a Schedule III controlled substance, and online prescribing without an in-person exam depends on a DEA rule that runs through December 31, 2026. Compare clinics on our testosterone hub.

The bottom line

For healthy men aged 19 to 39, normal total testosterone runs about 264 to 916 ng/dL, and it falls about 1% to 2% a year after 40, faster for free testosterone. Below 300 ng/dL with symptoms, confirmed on two morning tests, is the usual threshold for a treatment discussion. Read your result against your own lab’s range, and talk it through with a licensed clinician.

Questions, answered

What is a normal testosterone level for a man?

For healthy nonobese men aged 19 to 39, a large harmonized study put the normal range at 264 to 916 ng/dL, with a median of 531 ng/dL. Labs report their own reference range, so compare your result with the range printed on your report.

What testosterone level is considered low?

The American Urological Association uses a total testosterone below 300 ng/dL as a reasonable cut-off, combined with symptoms. Low testosterone is confirmed with at least two early-morning tests.

Does testosterone drop with age?

Yes, gradually. In the Massachusetts Male Aging Study of men aged 40 to 70, total testosterone fell 1.6% a year within the same men over 7 to 10 years, and free testosterone fell faster. Men in good health had androgen levels 10% to 15% higher.

Why does the time of day matter for a testosterone test?

Testosterone is higher in the morning, so guidelines and FDA labels call for morning samples. The Endocrine Society also recommends fasting and repeating a low result before diagnosing hypogonadism.

Sources

  1. Travison et al., Harmonized Reference Ranges for Circulating Testosterone Levels in Men of Four Cohort Studies, J Clin Endocrinol Metab 2017
  2. Feldman et al., Age trends in serum testosterone: longitudinal results from the Massachusetts Male Aging Study, J Clin Endocrinol Metab 2002
  3. Mulhall et al., Evaluation and Management of Testosterone Deficiency: AUA Guideline, J Urol 2018
  4. Bhasin et al., Testosterone Therapy in Men With Hypogonadism: Endocrine Society Clinical Practice Guideline, J Clin Endocrinol Metab 2018
  5. Lincoff et al., Cardiovascular Safety of Testosterone-Replacement Therapy (TRAVERSE), N Engl J Med 2023
  6. Pharmacia & Upjohn: Depo-Testosterone label (DailyMed, Aug 2026)
  7. Ascend Therapeutics: AndroGel 1.62% label (DailyMed, Nov 2025)
  8. Marius Pharmaceuticals: Kyzatrex label (DailyMed, Oct 2026)
  9. Verity Pharmaceuticals: Tlando label (DailyMed, Mar 2026)
  10. Antares Pharma: Xyosted label (DailyMed, Apr 2026)
  11. Henry Meds: Testosterone therapy eligibility (read Oct 18, 2026)

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